articleTop 1% cited
Subcutaneous Rotenone Exposure Causes Highly Selective Dopaminergic Degeneration and α-Synuclein Aggregation
Experimental Neurology · 2002 · Vol. 179(1) · pp. 9–16
Todd Sherer✉Jin-Ho Kim(Emory University)Ranjita Betarbet(Emory University)J. Timothy Greenamyre(Emory University)
Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolismNeurological disorders and treatmentsRotenoneDopaminergicOxidopamineParkinson's diseaseNeuNSubstantia nigraNeurodegenerationPharmacologyDopamineNeuroscience
MeSH terms
AnimalsCorpus StriatumDisease Models, AnimalDopamineInjections, SubcutaneousInsecticidesMaleNerve Tissue ProteinsNeural PathwaysNeuronsRats, Inbred LewRotenoneSubstantia NigraTimeTyrosine 3-Monooxygenase
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References
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
Nature Neuroscience · 2000 · 3,655 citations
ΔΨ<sub>m</sub>‐Dependent and ‐independent production of reactive oxygen species by rat brain mitochondria
Journal of Neurochemistry · 2001 · 594 citations
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Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · 522 citations
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Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats
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Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
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Abnormalities of the electron transport chain in idiopathic parkinson's disease
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