article Open AccessTop 1% cited
Pooled Association Tests for Rare Variants in Exon-Resequencing Studies
The American Journal of Human Genetics · 2010 · Vol. 86(6) · pp. 832–838
Alkes L. Price(Broad Institute)Gregory V. Kryukov(Broad Institute)Paul I.W. de Bakker(Broad Institute)Shaun Purcell(Broad Institute)Jeff Staples(Broad Institute)Lee‐Jen Wei(Harvard University)Shamil Sunyaev✉(Broad Institute)
Genetic Associations and EpidemiologyGenomics and Rare DiseasesGenomic variations and chromosomal abnormalitiesGeneticsGenetic associationStatistical powerBiologyPopulationPoolingComputational biologyStatistical hypothesis testingGeneGenotype
MeSH terms
ExonsGene FrequencyGenetics, PopulationHumansModels, GeneticGenetic VariationModels, StatisticalGenome-Wide Association Study
Funding
- National Institutes of Health
Citations
772
FWCI
49.23
field-weighted impact
References
20
Percentile
100%
vs. same field & year
Citations per year
Cited by
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References
Finding the missing heritability of complex diseases
Nature · 2009 · 8,468 citations
A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic
PLoS Genetics · 2009 · 1,166 citations
Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data
The American Journal of Human Genetics · 2008 · 1,605 citations
A method and server for predicting damaging missense mutations
Nature Methods · 2010 · 13,461 citations
Are Rare Variants Responsible for Susceptibility to Complex Diseases?
The American Journal of Human Genetics · 2001 · 1,223 citations
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