review Open AccessTop 1% cited
Metabolic pathways promoting cancer cell survival and growth
Nature Cell Biology · 2015 · Vol. 17(4) · pp. 351–359
Lindsey K. Boroughs✉(The University of Texas Southwestern Medical Center)Ralph J. DeBerardinis(Children's Medical Center)
Cancer, Hypoxia, and MetabolismEpigenetics and DNA MethylationMetabolism, Diabetes, and CancerMetabolic pathwayBiologyCell biologyReprogrammingCancer cellCancerCellFlexibility (engineering)MetabolismCell growth
MeSH terms
AnimalsCell SurvivalEnergy MetabolismGlucoseHumansNeoplasmsOncogenesCell ProliferationLipid MetabolismMiceMetabolic Networks and Pathways
Citations
1,487
FWCI
40.07
field-weighted impact
References
107
Percentile
100%
vs. same field & year
Citations per year
Cited by
Fundamentals of cancer metabolism
Science Advances · 2016 · 2,929 citations
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
Cell Metabolism · 2015 · 1,310 citations
The Warburg Effect: How Does it Benefit Cancer Cells?
Trends in Biochemical Sciences · 2016 · 4,978 citations
Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression
Cellular and Molecular Life Sciences · 2015 · 859 citations
References
Modulation of oxidative stress as an anticancer strategy
Nature Reviews Drug Discovery · 2013 · 3,495 citations
ROS Function in Redox Signaling and Oxidative Stress
Current Biology · 2014 · 6,564 citations
Cellular Fatty Acid Metabolism and Cancer
Cell Metabolism · 2013 · 2,104 citations
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Cancer Cell · 2010 · 1,966 citations
Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells
Cell Reports · 2014 · 581 citations
Self-consumption: the interplay of autophagy and apoptosis
Nature Reviews Molecular Cell Biology · 2014 · 2,136 citations
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
Cell Metabolism · 2008 · 4,067 citations
Metabolite profiles and the risk of developing diabetes
Nature Medicine · 2011 · 3,106 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.