review Open AccessTop 1% cited
Immunogenic cell death and DAMPs in cancer therapy
Nature reviews. Cancer · 2012 · Vol. 12(12) · pp. 860–875
Dmitri V. Krysko✉(Ghent University)Abhishek D. Garg(KU Leuven)Agnieszka Kaczmarek(Ghent University)Olga Krysko(Ghent University Hospital)Patrizia Agostinis(KU Leuven)Peter Vandenabeele(Ghent University)
Phagocytosis and Immune RegulationAutophagy in Disease and TherapyAdenosine and Purinergic SignalingCalreticulinImmunogenic cell deathImmunogenicityEndoplasmic reticulumProgrammed cell deathHMGB1Cancer cellUnfolded protein responseImmune systemCancer
MeSH terms
Adenosine TriphosphateAnimalsAntineoplastic AgentsEndoplasmic ReticulumHumansNeoplasmsPhagocytosisCell DeathReactive Oxygen SpeciesHMGB1 ProteinCalreticulin
Citations
3,009
FWCI
27.04
field-weighted impact
References
212
Percentile
100%
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Citations per year
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References
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
Cell Death and Differentiation · 2012 · 820 citations
Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates
Journal of Clinical Oncology · 2010 · 2,913 citations
Calreticulin exposure dictates the immunogenicity of cancer cell death
Nature Medicine · 2006 · 3,040 citations
Pattern recognition receptors and control of adaptive immunity
Immunological Reviews · 2008 · 718 citations
STATs in cancer inflammation and immunity: a leading role for STAT3
Nature reviews. Cancer · 2009 · 4,285 citations
The immune contexture in human tumours: impact on clinical outcome
Nature reviews. Cancer · 2012 · 4,857 citations
Endoplasmic reticulum stress responses
Cellular and Molecular Life Sciences · 2007 · 666 citations
Immunogenic death of colon cancer cells treated with oxaliplatin
Oncogene · 2009 · 1,118 citations
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