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Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer
Bioorganic & Medicinal Chemistry Letters · 2001 · Vol. 11(14) · pp. 1911–1914
Andrew Barker(AstraZeneca (United Kingdom))Keith H. Gibson✉(AstraZeneca (United Kingdom))Walter Grundy(AstraZeneca (United Kingdom))Andrew A. Godfrey(AstraZeneca (United Kingdom))Jeffrey J Barlow(AstraZeneca (United Kingdom))Mark P. Healy(AstraZeneca (United Kingdom))J.R. Woodburn(AstraZeneca (United Kingdom))Susan Ashton(AstraZeneca (United Kingdom))Brenda J Curry(AstraZeneca (United Kingdom))L. Scarlett(AstraZeneca (United Kingdom))Lianne Henthorn(AstraZeneca (United Kingdom))Laura M. Richards(AstraZeneca (United Kingdom))
HER2/EGFR in Cancer ResearchQuinazolinone synthesis and applicationsSynthesis and biological activityTyrosine kinaseEpidermal growth factor receptorChemistryPharmacologyEpidermal growth factorGrowth factor receptorTyrosine-kinase inhibitorPlatelet-derived growth factor receptorPharmacokineticsCancer
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