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Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

Free Radical Biology and Medicine · 2011 · Vol. 52(1) · pp. 59–69
Anabela P. RoloJoão S. TeodoroCarlos M. Palmeira
Liver Disease Diagnosis and TreatmentPeroxisome Proliferator-Activated ReceptorsAdipose Tissue and MetabolismOxidative stressNonalcoholic fatty liver diseaseLipogenesisReactive oxygen speciesHepatocyteMitochondrionChemistryEndocrinologyInsulin resistanceInternal medicine

MeSH terms

AnimalsDNA DamageFatty Acids, NonesterifiedFatty LiverHumansInflammationInsulin ResistanceMitochondriaOxidation-ReductionTriglyceridesLipid PeroxidationCytokinesReactive Oxygen SpeciesOxidative StressHepatocytes
Citations
920
FWCI
34.73
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References
225
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100%
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References
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
American Journal of Physiology-Cell Physiology · 1996 · 5,497 citations
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
Toxicology and Applied Pharmacology · 2006 · 998 citations
Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis
The American Journal of Gastroenterology · 2003 · 711 citations
Molecular mediators of hepatic steatosis and liver injury
Journal of Clinical Investigation · 2004 · 1,814 citations
Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes
Biochemical and Biophysical Research Communications · 2004 · 825 citations
Reactive oxygen species, cell signaling, and cell injury
Free Radical Biology and Medicine · 2000 · 1,010 citations
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