reviewTop 1% cited

Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress

Toxicology and Applied Pharmacology · 2006 · Vol. 212(2) · pp. 167–178

Anabela P. Rolo(University of Coimbra)Carlos M. Palmeira✉(University of Coimbra)

Adipose Tissue and Metabolism Mitochondrial Function and Pathology Advanced Glycation End Products researchPolyol pathwayOxidative stressMitochondrionInternal medicineDiabetes mellitusEndocrinologyBiologyGlycationMitochondrial DNAGlucose homeostasis

MeSH terms

AnimalsDiabetes MellitusGene Expression RegulationGlucoseHumansHyperglycemiaHypoglycemic AgentsInsulinMitochondriaUncoupling AgentsOxidative StressInsulin-Secreting Cells

Citations

998

FWCI

21.02

field-weighted impact

References

121

Percentile

100%

vs. same field & year

Citations per year

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References

High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

FEBS Letters · 1997 · 1,725 citations

Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections

Diabetes Care · 1998 · 6,328 citations

Biochemistry and molecular cell biology of diabetic complications

Nature · 2001 · 8,964 citations

Uncoupling: new approaches to an old problem of bioenergetics

Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · 884 citations

Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction?

Diabetes · 2003 · 1,465 citations

Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator

Endocrine Reviews · 2003 · 2,042 citations

Glucose Toxicity in β-Cells: Type 2 Diabetes, Good Radicals Gone Bad, and the Glutathione Connection

Diabetes · 2003 · 893 citations

Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes

Cardiovascular Research · 2004 · 989 citations

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