reviewTop 1% cited
Prodrugs: design and clinical applications
Nature Reviews Drug Discovery · 2008 · Vol. 7(3) · pp. 255–270
Jarkko Rautio✉(University of Eastern Finland)Hanna Kumpulainen(University of Eastern Finland)Tycho Heimbach(Tris Pharma (United States))Reza Oliyai(Gilead Sciences (United States))Doo-Man Oh(Amgen (United States))Tomi Järvinen(University of Eastern Finland)Jouko Savolainen
HIV/AIDS drug development and treatmentBiochemical and Molecular ResearchClick Chemistry and ApplicationsProdrugBiopharmaceuticalDrugPharmacologyDrug discoveryDrug developmentIn vivoPharmacokineticsChemistryMedicine
MeSH terms
AbsorptionAdministration, TopicalAnimalsBiological AvailabilityHumansParenteral NutritionProdrugsDrug DesignDrug Delivery Systems
Citations
1,565
FWCI
22.05
field-weighted impact
References
187
Percentile
100%
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Citations per year
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References
A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
Pharmaceutical Research · 1995 · 5,270 citations
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
European Journal of Cancer · 1998 · 1,233 citations
Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance
Clinical Pharmacology & Therapeutics · 2006 · 842 citations
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