reviewTop 1% cited
Mechanisms and consequences of activation of protein kinase B/Akt
Current Opinion in Cell Biology · 1998 · Vol. 10(2) · pp. 262–267
Julian Downward✉(The Honourable Society of Lincoln's Inn)
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase SignalingMetabolism, Diabetes, and CancerPleckstrin homology domainProtein kinase BAKT1AKT2BiologyProto-Oncogene Proteins c-aktCell biologyProtein kinase domainKinaseMitogen-activated protein kinase kinase
MeSH terms
AnimalsEnzyme ActivationGrowth SubstancesHumansInsulinModels, BiologicalProto-Oncogene ProteinsProtein Serine-Threonine KinasesProto-Oncogene Proteins c-akt
Citations
1,306
FWCI
44.30
field-weighted impact
References
52
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100%
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References
Mechanism of activation of protein kinase B by insulin and IGF-1.
The EMBO Journal · 1996 · 3,023 citations
Antiapoptotic Signalling by the Insulin-Like Growth Factor I Receptor, Phosphatidylinositol 3-Kinase, and Akt
Molecular and Cellular Biology · 1997 · 1,049 citations
Molecular alterations of the <i>AKT</i>2 oncogene in ovarian and breast carcinomas
International Journal of Cancer · 1995 · 836 citations
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
Cell · 1997 · 5,689 citations
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
Current Biology · 1997 · 2,824 citations
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