articleTop 1% cited
Characterization of Five Human cDNAs with Homology to the Yeast SIR2 Gene: Sir2-like Proteins (Sirtuins) Metabolize NAD and May Have Protein ADP-Ribosyltransferase Activity
Biochemical and Biophysical Research Communications · 1999 · Vol. 260(1) · pp. 273–279
Roy A. Frye✉(University of Pittsburgh Medical Center)
Sirtuins and Resveratrol in MedicineGenetic Neurodegenerative DiseasesPARP inhibition in cancer therapyNAD+ kinaseSirtuinSIRT2BiologyRecombinant DNABiochemistryMolecular biologyKluyveromyces lactisConserved sequenceSIRT3
MeSH terms
Amino Acid SequenceDNA-Binding ProteinsHistone DeacetylasesHumansMolecular Sequence DataMultienzyme ComplexesNucleotidyltransferasesPentosyltransferasesPoly(ADP-ribose) PolymerasesRecombinant ProteinsSaccharomyces cerevisiaeSerum Albumin, BovineTissue DistributionTrans-ActivatorsSequence Homology, Amino Acid
Funding
- University of Pittsburgh
Citations
805
FWCI
27.43
field-weighted impact
References
24
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100%
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