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Early Lineage Segregation between Epiblast and Primitive Endoderm in Mouse Blastocysts through the Grb2-MAPK Pathway

Developmental Cell · 2006 · Vol. 10(5) · pp. 615–624
Claire ChazaudYojiro YamanakaTony PawsonJanet Rossant
Pluripotent Stem Cells ResearchTissue Engineering and Regenerative MedicineMesenchymal stem cell researchBiologyEpiblastEndodermLineage (genetic)Cell biologyGastrulationEmbryoGeneticsEmbryonic stem cellEmbryogenesis

MeSH terms

Nanog Homeobox ProteinAnimalsBlastocystBlastomeresCell AggregationDNA-Binding ProteinsEndodermModels, BiologicalMorulaRNA, MessengerSignal TransductionHomeodomain ProteinsGene Expression Regulation, DevelopmentalCell LineageReceptor Protein-Tyrosine Kinases

Funding

  • Canadian Institutes of Health Research
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