review Open AccessTop 1% cited
The BCL-2 Family Reunion
Molecular Cell · 2010 · Vol. 37(3) · pp. 299–310
Jerry E. Chipuk✉(St. Jude Children's Research Hospital)Tudor Moldoveanu(St. Jude Children's Research Hospital)Fabien Llambi(St. Jude Children's Research Hospital)Melissa J. Parsons(St. Jude Children's Research Hospital)Douglas R. Green(St. Jude Children's Research Hospital)
Cell death mechanisms and regulationMitochondrial Function and PathologyCardiac Ischemia and ReperfusionBiologyBcl-2 familyContext (archaeology)MitochondrionFunction (biology)Cell biologyProtein familyApoptosisGeneticsProgrammed cell death
MeSH terms
Amino Acid SequenceAutophagyEndoplasmic ReticulumMultigene FamilyModels, BiologicalMolecular Sequence DataPermeabilitySignal TransductionSequence AlignmentApoptosisProto-Oncogene Proteins c-bcl-2Mitochondrial Membranes
Citations
1,404
FWCI
58.15
field-weighted impact
References
91
Percentile
100%
vs. same field & year
Citations per year
Cited by
Germ Cells Apoptosis during Spermatogenesis in Mammals
Journal of Entomology and Zoology Studies · 2015 · 5 citations
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
Cell Death and Disease · 2015 · 427 citations
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
Nature Reviews Molecular Cell Biology · 2013 · 3,145 citations
p53 Family and Cellular Stress Responses in Cancer
Frontiers in Oncology · 2014 · 289 citations
MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies
Cell Death and Disease · 2015 · 371 citations
Cancer drug resistance: an evolving paradigm
Nature reviews. Cancer · 2013 · 4,512 citations
Mitochondria and cell death: outer membrane permeabilization and beyond
Nature Reviews Molecular Cell Biology · 2010 · 2,483 citations
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cell Death and Differentiation · 2014 · 1,008 citations
References
Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein
Journal of Virology · 1998 · 1,116 citations
Roles of the Mammalian Mitochondrial Fission and Fusion Mediators Fis1, Drp1, and Opa1 in Apoptosis
Molecular Biology of the Cell · 2004 · 1,030 citations
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
Cancer Cell · 2002 · 1,634 citations
A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis
Developmental Cell · 2002 · 1,065 citations
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
Cancer Cell · 2006 · 1,217 citations
Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
Developmental Cell · 2008 · 1,175 citations
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
Cancer Cell · 2006 · 1,253 citations
The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells
Molecular Biology of the Cell · 2008 · 759 citations
Related articles
BCL-2 family proteins: changing partners in the dance towards death
Cell Death and Differentiation · 2017 · 1,530 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.