reviewTop 1% cited

Osteocytes, mechanosensing and Wnt signaling

Bone · 2008 · Vol. 42(4) · pp. 606–615

Lynda F. Bonewald✉(University of Missouri–Kansas City)Mark L. Johnson

Wnt/β-catenin signaling in development and cancer Connective tissue disorders research Bone Metabolism and DiseasesOsteocyteWnt signaling pathwayDKK1Cell biologyCrosstalkBone cellOsteoblastBone remodelingSclerostinChemistry

MeSH terms

AnimalsHumansModels, BiologicalOsteocytesStress, MechanicalBiosensing TechniquesSignal TransductionWnt Proteins

Citations

1,055

FWCI

28.41

field-weighted impact

References

125

Percentile

100%

vs. same field & year

Citations per year

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References

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A Mutation in the LDL Receptor–Related Protein 5 Gene Results in the Autosomal Dominant High–Bone-Mass Trait

The American Journal of Human Genetics · 2002 · 1,291 citations

Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone.

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Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β

Current Biology · 1998 · 844 citations

β-catenin is a target for the ubiquitin–proteasome pathway

The EMBO Journal · 1997 · 2,503 citations

Mechanical Strain Opens Connexin 43 Hemichannels in Osteocytes: A Novel Mechanism for the Release of Prostaglandin

Molecular Biology of the Cell · 2005 · 481 citations

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

Development · 1999 · 993 citations

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