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Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

Cell stem cell · 2010 · Vol. 7(1) · pp. 64–77
Payman Samavarchi‐TehraniAzadeh GolipourLaurent DavidHoon‐Ki SungTobias A. BeyerAlessandro DattiKnut WoltjenAndrás NagyJeffrey L. Wrana
Pluripotent Stem Cells ResearchRNA Interference and Gene DeliveryCRISPR and Genetic EngineeringReprogrammingBiologySomatic cellMesenchymal stem cellCell biologyEpithelial–mesenchymal transitionGenomicsFunctional genomicsTransition (genetics)Cell

MeSH terms

Kruppel-Like Factor 4Epithelial CellsFlow CytometryMesodermModels, BiologicalImmunoblottingProto-Oncogene Proteins c-mycBone Morphogenetic ProteinsReverse Transcriptase Polymerase Chain ReactionOligonucleotide Array Sequence AnalysisGenomicsRNA InterferenceRNA, Small InterferingOctamer Transcription Factor-3Kruppel-Like Transcription Factors

Funding

  • Canadian Institutes of Health Research
Citations
1,001
FWCI
37.06
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References
39
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100%
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