article Open AccessTop 1% cited
A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea‐predominant irritable bowel syndrome
Alimentary Pharmacology & Therapeutics · 2003 · Vol. 17(7) · pp. 895–904
H. J. Kim✉Michael Camilleri(Mayo Clinic)Sanna McKinzie(Mayo Clinic)Mary B. Lempke(Mayo Clinic)Duane D. Burton(Mayo Clinic)G. M. Thomforde(Mayo Clinic)Alan R. Zinsmeister(Mayo Clinic)
Abstract
VSL#3 appears to be promising in the relief of abdominal bloating in patients with diarrhoea-predominant irritable bowel syndrome. This is unrelated to an alteration in gastrointestinal or colonic transit.
Gastrointestinal motility and disordersGut microbiota and healthHelicobacter pylori-related gastroenterology studiesBloatingIrritable bowel syndromeMedicineInternal medicineAbdominal painPlaceboDefecationGastroenterologyDiarrheaRandomized controlled trial
MeSH terms
AdolescentAdultAgedColonic Diseases, FunctionalDiarrheaDouble-Blind MethodFemaleGastrointestinal TransitHumansMaleMiddle AgedPatient ComplianceTreatment OutcomeProbiotics
Funding
- National Institutes of Health
Citations
466
FWCI
20.90
field-weighted impact
References
38
Percentile
100%
vs. same field & year
Citations per year
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References
Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5‐HT<sub>3</sub> receptor antagonist
Alimentary Pharmacology & Therapeutics · 1999 · 372 citations
Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial
Gastroenterology · 2000 · 1,484 citations
Tegaserod, a 5‐HT<sub>4</sub> receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation
Alimentary Pharmacology & Therapeutics · 2001 · 464 citations
The Role of Probiotic Cultures in the Control of Gastrointestinal Health
Journal of Nutrition · 2000 · 925 citations
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