article Open AccessTop 1% cited
Tegaserod, a 5‐HT<sub>4</sub> receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation
Alimentary Pharmacology & Therapeutics · 2001 · Vol. 15(10) · pp. 1655–1666
S. Müller‐Lissner✉(Park-Klinik Weißensee)I. FumagalliKarna Dev Bardhan(Rotherham General Hospital)Fábio Pace(Luigi Sacco Hospital)E. Pecher(Novartis (Switzerland))Brigitte Nault(Novartis (Switzerland))P. Rüegg(Novartis (Switzerland))
Abstract
Based upon the results of this study, tegaserod offers rapid and sustained relief of the abdominal pain and constipation associated with irritable bowel syndrome. Tegaserod is also well tolerated.
Gastrointestinal motility and disordersDiet and metabolism studiesComplementary and Alternative Medicine StudiesTegaserodMedicineIrritable bowel syndromeBloatingConstipationPlaceboAbdominal painInternal medicineGastroenterologyPartial agonist
MeSH terms
AdultColonic Diseases, FunctionalConstipationDose-Response Relationship, DrugFemaleHumansIndolesMaleMiddle AgedSurveys and QuestionnairesReceptors, SerotoninAbdominal PainTreatment OutcomeSerotonin Receptor AgonistsReceptors, Serotonin, 5-HT4
Funding
- Novartis Pharma
Citations
464
FWCI
30.39
field-weighted impact
References
36
Percentile
100%
vs. same field & year
Citations per year
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References
Impact of irritable bowel syndrome on quality of life
Digestive Diseases and Sciences · 1996 · 295 citations
Functional bowel disorders and functional abdominal pain
Gut · 1999 · 2,388 citations
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