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Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5‐HT<sub>3</sub> receptor antagonist
Alimentary Pharmacology & Therapeutics · 1999 · Vol. 13(9) · pp. 1149–1159
Camilleri✉(Mayo Clinic)Mayer(University of California, Los Angeles)Drossman(University of North Carolina at Chapel Hill)Heath(Research Triangle Park Foundation)Dukes(University of North Carolina at Chapel Hill)David McSorley(Research Triangle Park Foundation)Kong(Research Triangle Park Foundation)Allen W. Mangel(Research Triangle Park Foundation)Northcutt(Research Triangle Park Foundation)
Abstract
In female irritable bowel syndrome patients with predominant diarrhoea or alternating constipation and diarrhoea, alosetron is effective in treatment of abdominal pain and discomfort and bowel-related symptoms.
Gastrointestinal motility and disordersMusic Therapy and HealthDiet and metabolism studiesMedicineIrritable bowel syndromePlaceboConstipationInternal medicineGastroenterologyAbdominal painDefecationPathology
MeSH terms
AdultCanadaCarbolinesColonic Diseases, FunctionalDiarrheaDose-Response Relationship, DrugDouble-Blind MethodFemaleGermanyUnited KingdomHumansMaleMiddle AgedNetherlandsSerotonin Antagonists
Citations
372
FWCI
15.10
field-weighted impact
References
36
Percentile
100%
vs. same field & year
Citations per year
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References
Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease
JNCI Journal of the National Cancer Institute · 1959 · 14,848 citations
Functional bowel disorders and functional abdominal pain
Gut · 1999 · 2,388 citations
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