reviewTop 1% cited
The complexity of p53 stabilization and activation
Cell Death and Differentiation · 2006 · Vol. 13(6) · pp. 941–950
Martin F. Lavin✉(University of Queensland)Nuri Gueven(QIMR Berghofer Medical Research Institute)
Cancer-related Molecular PathwaysUbiquitin and proteasome pathwaysCancer Research and TreatmentsProteasomeCell biologyUbiquitin ligaseMdm2P53 proteinDNA damageUbiquitinApoptosisSenescenceCell cycle
MeSH terms
AcetylationAnimalsCell CycleDNADNA DamageHumansMutagensPhosphorylationPoly(ADP-ribose) PolymerasesProtein KinasesProtein Processing, Post-TranslationalTumor Suppressor Protein p53ApoptosisUbiquitinProto-Oncogene Proteins c-mdm2
Funding
- National Health and Medical Research Council
- National Medical Research Council
Citations
691
FWCI
28.52
field-weighted impact
References
103
Percentile
100%
vs. same field & year
Citations per year
Cited by
p53 Family and Cellular Stress Responses in Cancer
Frontiers in Oncology · 2014 · 289 citations
References
Post‐translational modifications and activation of p53 by genotoxic stresses
European Journal of Biochemistry · 2001 · 1,073 citations
Regulation of p53 in response to DNA damage
Oncogene · 1999 · 995 citations
The p53 pathway: positive and negative feedback loops
Oncogene · 2005 · 1,985 citations
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
Annual Review of Biochemistry · 2004 · 3,280 citations
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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
FEBS Letters · 1997 · 1,932 citations
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