reviewTop 10% cited
NRF2-regulation in brain health and disease: Implication of cerebral inflammation
Neuropharmacology · 2013 · Vol. 79 · pp. 298–306
Mats Sandberg(University of Gothenburg)Jaspal Patil(University of Gothenburg)Barbara D’Angelo(University of Gothenburg)Stephen G. Weber(University of Pittsburgh)Carina Mallard✉(University of Gothenburg)
Genomics, phytochemicals, and oxidative stressNeuroinflammation and Neurodegeneration MechanismsInflammationOxidative stressTranscription factorRegulatorCell biologyNeuroinflammationAmyotrophic lateral sclerosisHistoneBiologyNeuroscience
MeSH terms
AnimalsBrainHumansInflammationSignal TransductionNF-E2-Related Factor 2
Funding
- European Commission
- Fondation Leducq
- Vetenskapsrådet
- Sahlgrenska Universitetssjukhuset
- National Institutes of Health
Citations
382
FWCI
8.82
field-weighted impact
References
131
Percentile
98%
vs. same field & year
Citations per year
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References
An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
Nature reviews. Neuroscience · 2006 · 4,065 citations
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
Molecular and Cellular Biology · 2003 · 1,204 citations
Systemic inflammation and disease progression in Alzheimer disease
Neurology · 2009 · 1,117 citations
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Nature Cell Biology · 2010 · 2,361 citations
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Genes & Development · 1999 · 3,543 citations
Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure
American Journal of Physiology-Renal Physiology · 2009 · 462 citations
Exercise builds brain health: key roles of growth factor cascades and inflammation
Trends in Neurosciences · 2007 · 2,207 citations
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