reviewTop 1% cited

Exercise builds brain health: key roles of growth factor cascades and inflammation

Trends in Neurosciences · 2007 · Vol. 30(9) · pp. 464–472

Carl W. Cotman✉(University of California, Irvine)Nicole C. Berchtold(University of California, Irvine)Lori‐Ann Christie(University of California, Irvine)

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Neurogenesis and neuroplasticity mechanisms Cancer-related cognitive impairment studies Apelin-related biomedical researchNeurodegenerationNeuroscienceSynaptic plasticityMechanism (biology)NeuroplasticityNeurogenesisBrain Structure and FunctionPsychologyPhysical exerciseEnvironmental enrichment

MeSH terms

AnimalsBrainDepressionHumansInflammationNerve Growth FactorsRisk FactorsExerciseIntercellular Signaling Peptides and Proteins

Funding

National Institute on Aging

Citations

2,207

FWCI

22.72

field-weighted impact

References

100

Percentile

100%

vs. same field & year

Citations per year

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References

Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

Journal of Neurochemistry · 2002 · 964 citations

Exercise Enhances Learning and Hippocampal Neurogenesis in Aged Mice

Journal of Neuroscience · 2005 · 2,069 citations

Cognitive impairment in major depression

European Journal of Pharmacology · 2009 · 448 citations

The Biology of Vascular Endothelial Growth Factor

Endocrine Reviews · 1997 · 4,356 citations

VEGF is necessary for exercise‐induced adult hippocampal neurogenesis

European Journal of Neuroscience · 2003 · 846 citations

The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.

Archives of Physical Medicine and Rehabilitation · 2004 · 1,222 citations

Exercise: a behavioral intervention to enhance brain health and plasticity

Trends in Neurosciences · 2002 · 2,670 citations

Fitness Effects on the Cognitive Function of Older Adults

Psychological Science · 2003 · 3,727 citations

Beneficial effects of physical exercise on neuroplasticity and cognition

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