reviewTop 10% cited
Nrf2 signaling and cell survival
Toxicology and Applied Pharmacology · 2009 · Vol. 244(1) · pp. 37–42
Suryakant Niture✉(University of Maryland, Baltimore)James W. Kaspar(University of Maryland, Baltimore)Jun Shen(University of Maryland, Baltimore)Anil K. Jaiswal(University of Maryland, Baltimore)
Genomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsSelenium in Biological SystemsCell biologyKEAP1Ubiquitin ligaseCytosolNuclear export signalPhosphorylationOxidative stressFYNSignal transducing adaptor proteinSignal transduction
MeSH terms
Kelch-Like ECH-Associated Protein 1Amino Acid SequenceAnimalsAntioxidantsBinding SitesCell SurvivalCytoskeletal ProteinsDrug ResistanceHomeostasisHumansMolecular Sequence DataNeoplasmsPhosphorylationSignal TransductionOxidative Stress
Funding
- National Institute of General Medical Sciences
- National Institute of Environmental Health Sciences
Citations
396
FWCI
8.74
field-weighted impact
References
101
Percentile
98%
vs. same field & year
Citations per year
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References
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
Nature Reviews Drug Discovery · 2008 · 1,820 citations
An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
Biochemical and Biophysical Research Communications · 1997 · 3,915 citations
Reactions of oxyl radicals with DNA
Free Radical Biology and Medicine · 1995 · 1,030 citations
Nrf2 signaling in coordinated activation of antioxidant gene expression
Free Radical Biology and Medicine · 2004 · 1,236 citations
Oxidants as Stimulators of Signal Transduction
Free Radical Biology and Medicine · 1997 · 1,374 citations
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
Molecular and Cellular Biology · 2003 · 1,204 citations
Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
Carcinogenesis · 2008 · 835 citations
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Genes & Development · 1999 · 3,543 citations
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