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Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts Type II diabetes independent of insulin resistance
Diabetologia · 2000 · Vol. 43(12) · pp. 1498–1506
C. Weyer✉(National Institutes of Health)James E. Foley(National Institutes of Health)Clifton Bogardus(National Institute of Diabetes and Digestive and Kidney Diseases)P. Antonio Tataranni(National Institute of Diabetes and Digestive and Kidney Diseases)Richard E. Pratley(National Institutes of Health)
Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and AdiposityInsulin resistanceObesityInternal medicineAdipocyteMedicineEndocrinologyType 2 diabetesDiabetes mellitusHuman physiologyAbdominal obesity
MeSH terms
AbdomenAdipose TissueAdultBlood GlucoseBody CompositionCross-Sectional StudiesDiabetes Mellitus, Type 2Fatty Acids, NonesterifiedFemaleFollow-Up StudiesGlucose Tolerance TestHumansHyperinsulinismInsulinInsulin Resistance
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788
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References
Obesity, Fat Distribution, and Weight Gain as Risk Factors for Clinical Diabetes in Men
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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
Journal of Clinical Investigation · 1999 · 1,945 citations
Adipose tissue as an endocrine and paracrine organ
International Journal of Obesity · 1998 · 989 citations
PPAR-gamma: adipogenic regulator and thiazolidinedione receptor.
Diabetes · 1998 · 1,733 citations
PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance
Molecular Cell · 1999 · 1,352 citations
Relation of Body Fat Distribution to Metabolic Complications of Obesity*
The Journal of Clinical Endocrinology & Metabolism · 1982 · 1,934 citations
Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid
The Journal of Clinical Endocrinology & Metabolism · 1998 · 1,134 citations
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