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Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor
Immunity · 2007 · Vol. 27(2) · pp. 281–295
Nikhil S. Joshi✉(Yale University)Weiguo Cui(Yale University)Anmol Chandele(Yale University)Heung Kyu Lee(Yale University)David Urso(Yale University)James Hagman(National Jewish Health)Laurent Gapin(National Jewish Health)Susan M. Kaech(Yale University)
Immune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesEffectorBiologyTranscription factorCell biologyInflammationCD8Transcription (linguistics)Expression (computer science)Cytotoxic T cellGenetics
MeSH terms
T-bet Transcription FactorAnimalsImmunologic MemoryInfectionsInflammationInterferon-gammaMice, Mutant StrainsReceptors, ImmunologicBiomarkersCytokinesCD8-Positive T-LymphocytesInterleukin-12Interleukin-15Receptors, Interleukin-7T-Box Domain Proteins
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References
Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo
Nature Immunology · 2000 · 1,578 citations
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
Nature Immunology · 2003 · 1,806 citations
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Nature Immunology · 2003 · 1,836 citations
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