review Open AccessTop 1% cited
Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
Nature Reviews Drug Discovery · 2014 · Vol. 13(9) · pp. 655–672
Samir Mitragotri✉(University of California, Santa Barbara)Paul A. Burke(BioVentures (United States))Róbert Langer(Massachusetts Institute of Technology)
Protein purification and stabilityTransgenic Plants and ApplicationsMonoclonal and Polyclonal Antibodies ResearchBiopharmaceuticalTransdermalDrug deliveryPolyethylene glycolPharmacologyMedicineNanotechnologyBiotechnologyChemistryBiology
MeSH terms
AnimalsBiopharmaceuticsChemistry, PharmaceuticalHumansDrug Delivery Systems
Funding
- National Institute for Health and Care Research
- National Institutes of Health
Citations
1,597
FWCI
49.97
field-weighted impact
References
205
Percentile
100%
vs. same field & year
Citations per year
Cited by
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Advanced Drug Delivery Reviews · 2015 · 4,151 citations
Trends in peptide drug discovery
Nature Reviews Drug Discovery · 2021 · 1,812 citations
Diverse Applications of Nanomedicine
ACS Nano · 2017 · 1,319 citations
The Current State of Peptide Drug Discovery: Back to the Future?
Journal of Medicinal Chemistry · 2017 · 1,075 citations
Controlled Drug Delivery Systems: Current Status and Future Directions
Molecules · 2021 · 1,527 citations
References
Controlled Delivery Systems for Proteins Based on Poly(Lactic/Glycolic Acid) Microspheres
Pharmaceutical Research · 1991 · 845 citations
Hyaluronic Acid Hydrogels for Biomedical Applications
Advanced Materials · 2011 · 2,047 citations
Hydrogen Bonding between Sugar and Protein Is Responsible for Inhibition of Dehydration-Induced Protein Unfolding
Archives of Biochemistry and Biophysics · 1999 · 535 citations
Doxil® — The first FDA-approved nano-drug: Lessons learned
Journal of Controlled Release · 2012 · 4,472 citations
Nasal drug delivery—possibilities, problems and solutions
Journal of Controlled Release · 2003 · 1,070 citations
Albumin as a versatile platform for drug half-life extension
Biochimica et Biophysica Acta (BBA) - General Subjects · 2013 · 467 citations
Cyclodextrin-based pharmaceutics: past, present and future
Nature Reviews Drug Discovery · 2004 · 1,947 citations
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Nature Biotechnology · 2011 · 4,710 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.