review Open AccessTop 1% cited
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Advanced Drug Delivery Reviews · 2015 · Vol. 99(Pt A) · pp. 28–51
Jung Soo Suk(Johns Hopkins University)Qingguo Xu(Johns Hopkins University)Nam‐Ho Kim(Johns Hopkins University)Justin Hanes(Johns Hopkins University)Laura M. Ensign✉(Johns Hopkins University)
RNA Interference and Gene DeliveryAdvanced Drug Delivery SystemsNanoparticle-Based Drug DeliveryPEGylationPEG ratioNanoparticleGene deliveryPolyethylene glycolDrug deliverySystemic administrationNanotechnologyAntibody opsonizationDrug
MeSH terms
AnimalsHumansPolyethylene GlycolsSurface PropertiesDrug Delivery SystemsGene Transfer TechniquesNanoparticles
Funding
- Foundation for the National Institutes of Health
Citations
4,151
FWCI
61.61
field-weighted impact
References
250
Percentile
100%
vs. same field & year
Citations per year
Cited by
Chitosan Derivatives and Their Application in Biomedicine
International Journal of Molecular Sciences · 2020 · 934 citations
Polymeric Nanoparticles in Gene Therapy: New Avenues of Design and Optimization for Delivery Applications
Polymers · 2019 · 333 citations
Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development
Journal of Clinical Medicine · 2020 · 516 citations
Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Advanced Science · 2023 · 481 citations
Liposomes: structure, composition, types, and clinical applications
Heliyon · 2022 · 1,294 citations
Green approaches in synthesising nanomaterials for environmental nanobioremediation: Technological advancements, applications, benefits and challenges
Environmental Research · 2021 · 532 citations
Thermo-responsive polymers: Applications of smart materials in drug delivery and tissue engineering
Materials Science and Engineering C · 2019 · 361 citations
Advances in oligonucleotide drug delivery
Nature Reviews Drug Discovery · 2020 · 1,897 citations
References
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes
FEBS Letters · 1990 · 2,006 citations
Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
Nature Nanotechnology · 2013 · 2,144 citations
Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
Nature Reviews Drug Discovery · 2014 · 1,597 citations
Sheddable Coatings for Long-Circulating Nanoparticles
Pharmaceutical Research · 2007 · 548 citations
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
Advanced Drug Delivery Reviews · 2008 · 1,734 citations
Mediating Tumor Targeting Efficiency of Nanoparticles Through Design
Nano Letters · 2009 · 1,476 citations
The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration
Colloids and Surfaces B Biointerfaces · 2000 · 363 citations
Stealth Me. PEG‐PLA Nanoparticles Avoid Uptake by the Mononuclear Phagocytes System
Journal of Pharmaceutical Sciences · 1995 · 630 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
