article Open AccessTop 1% cited
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
Cancer Cell · 2005 · Vol. 8(4) · pp. 299–309
Oriol Casanovas✉(University of California, San Francisco)Daniel J. HicklinGabriele Bergers(University of California, San Francisco)Douglas Hanahan(University of California, San Francisco)
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in CancerNeuroblastoma Research and TreatmentsCancer researchDrug resistanceIsletPancreatic cancerVEGF receptorsDrugStage (stratigraphy)Evasion (ethics)BiologyMedicine
MeSH terms
Fibroblast Growth FactorsHumansIslets of LangerhansNeovascularization, PathologicPancreatic NeoplasmsSignal TransductionDrug Resistance, NeoplasmReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor ACell Line, Tumor
Funding
- American Cancer Society
- National Cancer Institute
Citations
1,605
FWCI
22.39
field-weighted impact
References
52
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100%
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References
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
Nature Cell Biology · 2000 · 2,775 citations
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
Cell · 1996 · 6,874 citations
The biology of VEGF and its receptors
Nature Medicine · 2003 · 9,519 citations
Regulation of angiogenesis by hypoxia: role of the HIF system
Nature Medicine · 2003 · 2,499 citations
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
Cancer Cell · 2003 · 1,293 citations
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
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