review Open AccessTop 1% cited
Mechanisms of tau-induced neurodegeneration
Acta Neuropathologica · 2009 · Vol. 118(1) · pp. 53–69
Khalid Iqbal✉(New York State Office for People With Developmental Disabilities)Fei Liu(New York State Office for People With Developmental Disabilities)Cheng‐Xin Gong(New York State Office for People With Developmental Disabilities)Alejandra del C. Alonso(College of Staten Island)Inge Grundke‐Iqbal(New York State Office for People With Developmental Disabilities)
Alzheimer's disease research and treatmentsPrion Diseases and Protein MisfoldingMicrotubule and mitosis dynamicsNeurodegenerationHyperphosphorylationProtein phosphatase 2Axoplasmic transportTauopathyPhosphataseNeuroscienceCell biologyPhosphorylationCorticobasal degeneration
MeSH terms
Alzheimer DiseaseAnimalsBrainDementiaDown SyndromeGlucoseHumansMicrotubule-Associated ProteinsMicrotubulesMutationNerve DegenerationPhosphorylationProtein ConformationAmyloid beta-PeptidesNeurofibrillary Tangles
Funding
- National Institutes of Health
Citations
626
FWCI
30.37
field-weighted impact
References
221
Percentile
100%
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Citations per year
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References
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Neuron · 2003 · 4,102 citations
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Nature Reviews Drug Discovery · 2008 · 1,820 citations
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
Neurobiology of Aging · 2003 · 997 citations
Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
Current Biology · 1996 · 1,319 citations
Molecular cloning and expression of glycogen synthase kinase-3/factor A.
The EMBO Journal · 1990 · 1,349 citations
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
European Journal of Neuroscience · 2005 · 744 citations
Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome
Annals of Neurology · 1985 · 1,160 citations
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