reviewTop 1% cited
Role of Tyrosine Kinase Inhibitors in Cancer Therapy
Journal of Pharmacology and Experimental Therapeutics · 2005 · Vol. 315(3) · pp. 971–979
Amit Arora✉(Nebraska Medical Center)Eric Scholar
Chronic Myeloid Leukemia TreatmentsHER2/EGFR in Cancer ResearchPI3K/AKT/mTOR signaling in cancerLapatinibMedicineGefitinibTyrosine kinaseErlotinibPharmacologySorafenibTargeted therapyCancer researchCancer
MeSH terms
Antineoplastic AgentsEnzyme InhibitorsHumansNeoplasmsProtein-Tyrosine KinasesMolecular StructureSignal TransductionProtein Kinase Inhibitors
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References
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
Nature Medicine · 1996 · 3,643 citations
Cell Signaling by Receptor Tyrosine Kinases
Cell · 2010 · 7,809 citations
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
New England Journal of Medicine · 2004 · 11,455 citations
BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis
Cancer Research · 2004 · 4,006 citations
Multi-Institutional Randomized Phase II Trial of Gefitinib for Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer
Journal of Clinical Oncology · 2003 · 2,883 citations
Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
Journal of Pharmacology and Experimental Therapeutics · 2000 · 1,280 citations
Mutations of the BRAF gene in human cancer
Nature · 2002 · 10,619 citations
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