article Open AccessTop 1% cited
The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors
Molecular Cell · 2004 · Vol. 14(3) · pp. 395–403
Trevor N. Stitt✉(Regeneron (United States))Doreen DrujanBrian ClarkeFrank J. PanaroYekatarina TimofeyvaWilliam O. KlineMichael GonzalezGeorge D. YancopoulosDavid J. Glass
Muscle Physiology and DisordersAdipose Tissue and MetabolismSirtuins and Resveratrol in MedicineProtein kinase BBiologyFOXO1PI3K/AKT/mTOR pathwayPhosphorylationMuscle atrophyUbiquitinDownregulation and upregulationMuscle hypertrophyCell biology
MeSH terms
Tripartite Motif ProteinsForkhead Box Protein O1AnimalsCell LineDenervationDexamethasoneGlucocorticoidsInsulin-Like Growth Factor IMuscle ProteinsMuscular AtrophyMutationPhosphorylationProto-Oncogene ProteinsRNA, MessengerTranscription Factors
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References
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