reviewTop 1% cited
Intrinsically unstructured proteins and their functions
Nature Reviews Molecular Cell Biology · 2005 · Vol. 6(3) · pp. 197–208
H. Jane Dyson✉(Scripps Research Institute)Peter E. Wright(Scripps Research Institute)
Protein Structure and DynamicsEnzyme Structure and FunctionRNA and protein synthesis mechanismsComputational biologyENCODEFolding (DSP implementation)Intrinsically disordered proteinsSequence (biology)Function (biology)Protein foldingGenomeBiologyGene
MeSH terms
HumansNuclear ProteinsNucleic AcidsProtein BindingProtein Processing, Post-TranslationalProteinsTrans-ActivatorsTumor Suppressor Protein p53Protein Structure, TertiaryCREB-Binding Protein
Citations
3,843
FWCI
66.72
field-weighted impact
References
129
Percentile
100%
vs. same field & year
Citations per year
Cited by
A decade and a half of protein intrinsic disorder: Biology still waits for physics
Protein Science · 2013 · 492 citations
The Enigmatic LEA Proteins and Other Hydrophilins
PLANT PHYSIOLOGY · 2008 · 892 citations
Functional Anthology of Intrinsic Disorder. 1. Biological Processes and Functions of Proteins with Long Disordered Regions
Journal of Proteome Research · 2007 · 564 citations
The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease
Biochemical Society Transactions · 2016 · 405 citations
Disorder and Sequence Repeats in Hub Proteins and Their Implications for Network Evolution
Journal of Proteome Research · 2006 · 344 citations
Intrinsically disordered proteins in cellular signalling and regulation
Nature Reviews Molecular Cell Biology · 2014 · 2,444 citations
Sensitivity of secondary structure propensities to sequence differences between α‐ and γ‐synuclein: Implications for fibrillation
Protein Science · 2006 · 735 citations
Prediction of Protein Binding Regions in Disordered Proteins
PLoS Computational Biology · 2009 · 642 citations
References
CBP/p300 in cell growth, transformation, and development
Genes & Development · 2000 · 1,757 citations
The p53 pathway
The Journal of Pathology · 1999 · 1,303 citations
Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm
Journal of Molecular Biology · 1999 · 2,966 citations
Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life
Journal of Molecular Biology · 2004 · 2,041 citations
Sequence complexity of disordered protein
Proteins Structure Function and Bioinformatics · 2000 · 1,806 citations
Intrinsic Disorder and Protein Function
Biochemistry · 2002 · 1,727 citations
Why are ?natively unfolded? proteins unstructured under physiologic conditions?
Proteins Structure Function and Bioinformatics · 2000 · 2,086 citations
Natively unfolded proteins: A point where biology waits for physics
Protein Science · 2002 · 1,811 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.