articleTop 1% cited

Polymer physics of intracellular phase transitions

Nature Physics · 2015 · Vol. 11(11) · pp. 899–904

Clifford P. Brangwynne✉(Princeton University)Péter Tompa(HUN-REN Research Centre for Natural Sciences)Rohit V. Pappu(Washington University in St. Louis)

View via DOI Publisher page

RNA Research and Splicing Nuclear Structure and Function RNA and protein synthesis mechanismsIntracellularOrganelleMembraneCompartment (ship)Phase (matter)BiophysicsP-bodiesVesiclePhysicsPhase transition

Funding

National Science Foundation
Fonds Wetenschappelijk Onderzoek
National Institutes of Health

Citations

1,621

FWCI

31.03

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Recent progress in the science of complex coacervation

Soft Matter · 2020 · 647 citations

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

eLife · 2017 · 747 citations

Distinct stages in stress granule assembly and disassembly

eLife · 2016 · 845 citations

RNA polymerase II clustering through carboxy-terminal domain phase separation

Nature Structural & Molecular Biology · 2018 · 632 citations

α-Synuclein aggregation nucleates through liquid–liquid phase separation

Nature Chemistry · 2020 · 858 citations

Biomolecular condensates: organizers of cellular biochemistry

Nature Reviews Molecular Cell Biology · 2017 · 6,142 citations

Sequence determinants of protein phase behavior from a coarse-grained model

PLoS Computational Biology · 2018 · 741 citations

Pi-Pi contacts are an overlooked protein feature relevant to phase separation

eLife · 2018 · 949 citations

References

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

Molecular Cell · 2015 · 1,643 citations

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

eLife · 2015 · 597 citations

Some Properties of Solutions of Long-chain Compounds.

The Journal of Physical Chemistry · 1942 · 1,340 citations

Intrinsically disordered proteins in cellular signalling and regulation

Nature Reviews Molecular Cell Biology · 2014 · 2,444 citations

Biogenesis and function of nuclear bodies

Trends in Genetics · 2011 · 680 citations

Thermodynamics of High Polymer Solutions

The Journal of Chemical Physics · 1942 · 4,296 citations

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

Molecular Cell · 2015 · 1,889 citations

Phase transitions of multivalent proteins can promote clustering of membrane receptors

eLife · 2014 · 621 citations

Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.