article Open AccessTop 1% cited
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
Molecular Cell · 2015 · Vol. 60(2) · pp. 208–219
Yuan Lin✉(Howard Hughes Medical Institute)David S.W. Protter(University of Colorado Boulder)Michael K. Rosen(Howard Hughes Medical Institute)Roy Parker(Howard Hughes Medical Institute)
RNA Research and SplicingLipid metabolism and biosynthesisIcing and De-icing TechnologiesBiologyRNARNA-binding proteinCell biologyBiophysicsBiochemistryGene
MeSH terms
Heterogeneous Nuclear Ribonucleoprotein A1AmyloidCytoplasmic GranulesEscherichia coliHumansPolyethylene GlycolsProtein BindingRecombinant ProteinsRNASodium ChlorideSolutionsOrganellesGene ExpressionProtein Structure, TertiaryMolecular Mimicry
Funding
- Howard Hughes Medical Institute
- National Institutes of Health
Citations
1,643
FWCI
53.33
field-weighted impact
References
47
Percentile
100%
vs. same field & year
Citations per year
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References
Principles of polymer chemistry
Choice Reviews Online · 1995 · 15,274 citations
Eukaryotic Stress Granules: The Ins and Outs of Translation
Molecular Cell · 2009 · 1,481 citations
<b>Stress Granule Assembly Is Mediated by Prion-like Aggregation of TIA-1</b>
Molecular Biology of the Cell · 2004 · 994 citations
Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
Molecular Cell · 2015 · 1,889 citations
Phase transitions of multivalent proteins can promote clustering of membrane receptors
eLife · 2014 · 621 citations
Principles of Polymer Chemistry.
Journal of the American Chemical Society · 1954 · 16,608 citations
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