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Intrinsically disordered proteins in cellular signalling and regulation

Nature Reviews Molecular Cell Biology · 2014 · Vol. 16(1) · pp. 18–29

Peter E. Wright✉(Scripps Research Institute)H. Jane Dyson(Scripps Research Institute)

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RNA Research and Splicing RNA and protein synthesis mechanisms Protein Structure and DynamicsSignallingIntrinsically disordered proteinsCell biologyOrganelleComputational biologyRNA splicingBiologyCytoplasmMechanism (biology)Chemistry

MeSH terms

AnimalsHumansOrgan SpecificityProtein Processing, Post-TranslationalSignal TransductionAlternative SplicingMultiprotein ComplexesIntrinsically Disordered Proteins

Funding

National Institutes of Health

Citations

2,444

FWCI

51.25

field-weighted impact

References

149

Percentile

100%

vs. same field & year

Citations per year

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References

Intrinsically unstructured proteins and their functions

Nature Reviews Molecular Cell Biology · 2005 · 3,843 citations

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

Journal of Molecular Biology · 1999 · 2,966 citations

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

Trends in Biochemical Sciences · 2007 · 1,072 citations

Intrinsic Disorder and Protein Function

Biochemistry · 2002 · 1,727 citations

Prediction of Protein Binding Regions in Disordered Proteins

PLoS Computational Biology · 2009 · 642 citations

Ghrelin: Structure and Function

Physiological Reviews · 2005 · 2,790 citations

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