article Open AccessTop 1% cited
Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain
Nature Structural & Molecular Biology · 2019 · Vol. 26(7) · pp. 637–648
Anastasia C. Murthy(Brown University)Gregory L. Dignon(Lehigh University)Yelena Kan(Max Planck Institute for Polymer Research)Gül H. Zerze(Lehigh University)Sapun H. Parekh(Max Planck Institute for Polymer Research)Jeetain Mittal(Lehigh University)Nicolas L. Fawzi✉(Brown University)
RNA Research and SplicingRNA and protein synthesis mechanismsRNA modifications and cancerChemistryIntrinsically disordered proteinsResidue (chemistry)BiophysicsRNARaman spectroscopyLiquid liquidHydrogen bondNuclear magnetic resonance spectroscopyCrystallography
MeSH terms
Protein DomainsHumansHydrogen BondingModels, MolecularProtein ConformationProtein Structure, SecondaryRNA-Binding Protein FUSPhase TransitionHydrophobic and Hydrophilic InteractionsIntrinsically Disordered Proteins
Funding
- National Science Foundation
- U.S. Department of Energy
- Brown University
- Deutsche Forschungsgemeinschaft
- Office of Science
- National Institute of General Medical Sciences
- Basic Energy Sciences
Citations
767
FWCI
28.52
field-weighted impact
References
68
Percentile
100%
vs. same field & year
Citations per year
References
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Trends in Biochemical Sciences · 2002 · 2,056 citations
Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
Molecular Cell · 2015 · 1,889 citations
Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association
Journal of Chemical Theory and Computation · 2014 · 706 citations
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