articleTop 1% cited

Toll-like receptors control activation of adaptive immune responses

Nature Immunology · 2001 · Vol. 2(10) · pp. 947–950

Markus Schnare✉(Yale University)Gregory M. Barton(Howard Hughes Medical Institute)Agnieszka Czopik Holt(Yale University)Kiyoshi Takeda(Osaka University)Shizuo Akira(Osaka University)Ruslan Medzhitov(Yale University)

View via DOI Publisher page

Immune Response and Inflammation Immune Cell Function and Interaction NF-κB Signaling PathwaysInnate immune systemImmune systemAcquired immune systemBiologyPattern recognition receptorImmune receptorImmunityEffectorCCL18Immunology

MeSH terms

AnimalsAntigens, DifferentiationCell DifferentiationCells, CulturedDendritic CellsImmunoglobulinsInterferon-gammaLymphocyte ActivationMembrane GlycoproteinsPhenotypeReceptors, Cell SurfaceReceptors, ImmunologicMice, KnockoutTh1 CellsTh2 Cells

Funding

Howard Hughes Medical Institute

Citations

1,361

FWCI

28.60

field-weighted impact

References

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100%

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Citations per year

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References

Dendritic cells and the control of immunity

Nature · 1998 · 14,273 citations

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

Immunity · 1999 · 2,066 citations

MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways

Molecular Cell · 1998 · 1,557 citations

Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components

Immunity · 1999 · 3,351 citations

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Immunity · 1998 · 2,015 citations

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