reviewTop 1% cited

Toll-like receptor control of the adaptive immune responses

Nature Immunology · 2004 · Vol. 5(10) · pp. 987–995

Akiko Iwasaki✉(Howard Hughes Medical Institute)Ruslan Medzhitov(Yale University)

Immune Response and Inflammation Immunotherapy and Immune Responses Immune Cell Function and InteractionImmune systemBiologyAcquired immune systemInnate immune systemImmunologyToll-like receptorPattern recognition receptorReceptorDendritic cellImmunity

MeSH terms

Adaptation, PhysiologicalAnimalsAntibody FormationB-LymphocytesCell MovementDendritic CellsHumansImmunity, InnateInterferon Type ILymphocyte ActivationMembrane GlycoproteinsReceptors, Cell SurfaceT-LymphocytesStromal CellsToll-Like Receptors

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References

Toll-like receptors control activation of adaptive immune responses

Nature Immunology · 2001 · 1,361 citations

Dendritic cells and the control of immunity

Nature · 1998 · 14,273 citations

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

Nature Immunology · 2001 · 2,508 citations

Differential Expression and Regulation of Toll-Like Receptors (TLR) in Human Leukocytes: Selective Expression of TLR3 in Dendritic Cells

The Journal of Immunology · 2000 · 1,050 citations

Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α<sup>+</sup> DC correlates with unresponsiveness to imidazoquinolines

European Journal of Immunology · 2003 · 535 citations

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

European Journal of Immunology · 2001 · 775 citations

Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>

Science · 2003 · 8,062 citations

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