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Timothy M. Willson

Research Triangle Park FoundationORCID https://orcid.org/0000-0003-4181-8223

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Impact (2-yr)

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Top Publications

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Journal of Biological Chemistry19953,617 citations

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Molecular Cell20001,884 citations

The PPARs: From Orphan Receptors to Drug Discovery

Journal of Medicinal Chemistry20001,799 citationsFirst authorCorresponding

6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

Journal of Medicinal Chemistry2002725 citations

The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution

Molecular Endocrinology2000558 citations

Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity

Bioorganic & Medicinal Chemistry Letters2003311 citations

Timothy M. Willson · Scinovex