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Hans Clevers

Royal Netherlands Academy of Arts and SciencesORCID https://orcid.org/0000-0002-3077-5582
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Top Publications

Wnt/β-Catenin Signaling in Development and Disease
Cell20065,519 citationsFirst authorCorresponding
Wnt/β-Catenin Signaling and Disease
Cell20125,472 citationsFirst authorCorresponding
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
Gastroenterology20113,707 citationsCorresponding
Cancer stem cells revisited
Nature Medicine20172,766 citationsCorresponding
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
The Journal of Experimental Medicine20172,400 citations
Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation
Developmental Cell20051,545 citations
Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro
Cell stem cell20101,530 citations
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
Cell stem cell20131,381 citationsCorresponding
Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors
Molecular and Cellular Biology20021,033 citations
The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
Cell stem cell2011931 citations
Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients
Science Translational Medicine2019788 citations
Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines
Breast Cancer Research and Treatment2009303 citations