article Open AccessTop 1% cited
Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro
Cell stem cell · 2010 · Vol. 6(1) · pp. 25–36
Nick Barker✉(Hubrecht Institute for Developmental Biology and Stem Cell Research)Meritxell Huch(Hubrecht Institute for Developmental Biology and Stem Cell Research)Pekka Kujala(The Netherlands Cancer Institute)Marc van de Wetering(Hubrecht Institute for Developmental Biology and Stem Cell Research)Hugo J.G. Snippert(Hubrecht Institute for Developmental Biology and Stem Cell Research)Johan H. van Es(Hubrecht Institute for Developmental Biology and Stem Cell Research)Toshiro Sato(Hubrecht Institute for Developmental Biology and Stem Cell Research)Daniel E. Stange(Hubrecht Institute for Developmental Biology and Stem Cell Research)Harry Begthel(Hubrecht Institute for Developmental Biology and Stem Cell Research)Maaike van den Born(Hubrecht Institute for Developmental Biology and Stem Cell Research)Esther Danenberg(Hubrecht Institute for Developmental Biology and Stem Cell Research)Stieneke van den Brink(Hubrecht Institute for Developmental Biology and Stem Cell Research)Jeroen Korving(Hubrecht Institute for Developmental Biology and Stem Cell Research)Arie Abo(UNAVCO)Peter J. Peters(The Netherlands Cancer Institute)Nicholas A. WrightRichard Poulsom(The Honourable Society of Lincoln's Inn)Hans Clevers(Hubrecht Institute for Developmental Biology and Stem Cell Research)
Cancer Cells and MetastasisDigestive system and related healthEpigenetics and DNA MethylationBiologyLGR5Stem cellIn vitroStomachCell biologyCancer stem cellGeneticsBiochemistry
MeSH terms
AgingAnimalsCell DifferentiationCells, CulturedGastric MucosaGene Expression RegulationMice, TransgenicStem CellsStomachBiomarkersCell LineageGene Expression ProfilingReceptors, G-Protein-CoupledMice
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References
Generalized lacZ expression with the ROSA26 Cre reporter strain
Nature Genetics · 1999 · 4,871 citations
Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors
Molecular and Cellular Biology · 2002 · 1,033 citations
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