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David N. Louis

Massachusetts General HospitalORCID https://orcid.org/0000-0002-9423-4099
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Top Publications

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
Acta Neuropathologica201615,741 citationsFirst authorCorresponding
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
New England Journal of Medicine200411,455 citations
The 2007 WHO Classification of Tumours of the Central Nervous System
Acta Neuropathologica20074,566 citationsFirst authorCorresponding
Malignant astrocytic glioma: genetics, biology, and paths to treatment
Genes & Development20072,299 citations
AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients
Cancer Cell20071,760 citations
Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas
JNCI Journal of the National Cancer Institute19981,615 citations
Human Keratinocytes That Express hTERT and Also Bypass a p16<sup>INK4a</sup>-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics
Molecular and Cellular Biology20001,089 citations
Inertial Focusing for Tumor Antigen–Dependent and –Independent Sorting of Rare Circulating Tumor Cells
Science Translational Medicine20131,071 citations
Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
Acta Neuropathologica20111,020 citations
cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”
Acta Neuropathologica2018891 citations
cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas
Acta Neuropathologica2020515 citations
Novel, improved grading system(s) for IDH-mutant astrocytic gliomas
Acta Neuropathologica2018463 citations