Formulation and evaluation of herbal gummies from Bacopa monnieri and walnut oil for memory enhancing

Abstract

The growing worldwide incidence of cognitive impairment and memory disorders has led to seeking safer and more effective natural substitutes for traditional nootropics. One such widely recognized Ayurvedic herb is Bacopa monnieri, also referred to as Brahmi. The herb is well-documented to possess memory-enhancing, neuroprotective, and adaptogenic activity. Its major active ingredients, the bacosides, have been identified to facilitate synaptic communication and enhance neuronal repair. Adding to this, walnut oil contains alpha-linolenic acid (ALA), an omega-3 fatty acid of plant origin, and polyphenols which contribute to brain function via anti-inflammatory and antioxidant effects. The objective of this study was to develop a new herbal gummy supplement from Bacopa monnieri extract and walnut oil to provide a taste-friendly, user-friendly dose form that is ideal for children and the elderly. The Bacopa monnieri herbal extract was procured through Soxhlet extraction with ethanol as the solvent to ensure the retention of important phytoconstituents. Cold-pressed walnut oil was added as a lipid-based memory booster. Gelatin was chosen as the gelling agent owing to its thermos-reversible and biocompatible nature, and other excipients such as sweeteners, citric acid, and flavouring agents were optimized to enhance acceptability and stability. The gummy product was prepared through the fusion process for homogenous blending and appropriate moulding. The outcome was a uniform, visually pleasing herbal gummy that may be used as a novel vehicle for cognitive health supplementation. This product is a promising avenue toward natural, safe, and non-invasive remedy for improving memory and brain function.