DMXL1 could be a potential candidate gene for semen quality in Holstein Friesian bulls

Abstract

The herd's overall financial success is closely tied to the reproductive efficiency of the breeding bulls. Reduced reproductive efficiency in dairy cattle often arises due to the subfertility or infertility of the breeding bulls. In this study, our main focus is on identifying candidate genes containing SNPs within the QTL region, with the goal of using them as markers to predict semen quality. Our study reports the relationship between DMXL1 gene and sperm motility in cattle bulls. Diverse studies emphasized the significance of DMXL1 in various cellular processes and pathways, encompassing cell cycle regulation, cell proliferation, and signal transduction. Further investigation into the DMXL1 gene could offer valuable insights and potentially position it as a candidate gene for semen quality in breeding bulls.