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Flavonoids a Bioactive Compound from Medicinal Plants and Its Therapeutic Applications

BioMed Research International · 2022 · Vol. 2022(1) · pp. 5445291–5445291
Arpita RoyAriba KhanIrfan AhmadSaad AlghamdiBodour S. RajabAhmad O. BabalghithMohammad Y. AlshahraniSaiful IslamMd. Rabiul Islam

Abstract

Plants generally secrete secondary metabolites in response to stress. These secondary metabolites are very useful for humankind as they possess a wide range of therapeutic activities. Secondary metabolites produced by plants include alkaloids, flavonoids, terpenoids, and steroids. Flavonoids are one of the classes of secondary metabolites of plants found mainly in edible plant parts such as fruits, vegetables, stems, grains, and bark. They are synthesized by the phenylpropanoid pathway. Flavonoids possess antibacterial, antiviral, antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic properties. Due to their various therapeutic applications, various pharmaceutical companies have exploited different plants for the production of flavonoids. To overcome this situation, various biotechnological strategies have been incorporated to improve the production of different types of flavonoids. In this review, we have highlighted the various types of flavonoids, their biosynthesis, properties, and different strategies to enhance the production of flavonoids.

Phytochemicals and Antioxidant ActivitiesNatural Antidiabetic Agents StudiesMoringa oleifera research and applicationsPhenylpropanoidTerpenoidMedicinal plantsAntioxidantBiologyBark (sound)Traditional medicineChemistryPolyphenolSecondary metabolism

MeSH terms

AlkaloidsAnti-Inflammatory AgentsFlavonoidsPlants, MedicinalTerpenes

Funding

  • Society of University Surgeons Foundation
  • King Khalid University
  • Sharda University
Citations
506
FWCI
34.93
field-weighted impact
References
57
Percentile
100%
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Citations per year
Cited by
Pharmacological and pharmaceutical aspects of herbal medicines: A review
International Journal of Herbal Medicine · 2025 · 1 citations
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