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JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects
Drugs · 2017 · Vol. 77(5) · pp. 521–546
Shubhasree Banerjee✉(National Institute of Arthritis and Musculoskeletal and Skin Diseases)Ann Biehl(National Institutes of Health Clinical Center)Massimo Gadina(National Institute of Arthritis and Musculoskeletal and Skin Diseases)Sarfaraz Hasni(National Institutes of Health)Daniella M. Schwartz(National Institutes of Health)
Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and TherapiesChronic Lymphocytic Leukemia ResearchTofacitinibMedicineJanus kinaseImmunologystatRheumatoid arthritisJAK-STAT signaling pathwayAutoimmunityRuxolitinibSignal transduction
MeSH terms
Autoimmune DiseasesHumansInflammationSignal TransductionProtein Kinase InhibitorsSTAT Transcription FactorsJanus Kinases
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References
IL-22 Increases the Innate Immunity of Tissues
Immunity · 2004 · 1,333 citations
Cytokines in inflammatory bowel disease
Nature reviews. Immunology · 2014 · 2,571 citations
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Nature Genetics · 2010 · 2,560 citations
JAKS AND STATS: Biological Implications
Annual Review of Immunology · 1998 · 1,808 citations
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