reviewTop 1% cited
Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition
Molecular and Cellular Endocrinology · 2017 · Vol. 451 · pp. 1–14
Bernd Groner✉(Georg Speyer Haus)Viktoria von Manstein(Georg Speyer Haus)
Cytokine Signaling Pathways and InteractionsCancer Mechanisms and TherapyPI3K/AKT/mTOR signaling in cancerstatJAK-STAT signaling pathwaySTAT5Cancer researchBiologySTAT3Signal transductionEpigeneticsTumor microenvironmentCancer cell
MeSH terms
Antineoplastic AgentsHumansImmunotherapyNeoplasm InvasivenessNeoplasmsNeoplastic Stem CellsSignal TransductionGene Expression Regulation, NeoplasticCell ProliferationSTAT Transcription FactorsJanus KinasesEpithelial-Mesenchymal TransitionMolecular Targeted TherapyTumor Microenvironment
Funding
- Bundesministerium für Gesundheit
- Hessisches Ministerium für Wissenschaft und Kunst
Citations
312
FWCI
13.31
field-weighted impact
References
140
Percentile
99%
vs. same field & year
Citations per year
Cited by
JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression
Cancers · 2019 · 709 citations
References
The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours
British Journal of Cancer · 2015 · 635 citations
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Nature reviews. Cancer · 2014 · 2,100 citations
STATs in cancer inflammation and immunity: a leading role for STAT3
Nature reviews. Cancer · 2009 · 4,285 citations
Annual Report to the Nation on the status of cancer, 1975‐2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer
Cancer · 2013 · 1,253 citations
Constitutive activation of <scp>STAT</scp>3 in breast cancer cells: A review
International Journal of Cancer · 2015 · 621 citations
STAT3 Target Genes Relevant to Human Cancers
Cancers · 2014 · 523 citations
Erratum to: JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects
Drugs · 2017 · 593 citations
JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects
Drugs · 2017 · 1,151 citations
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