A clinical evaluation study of single spin vs double spin intra-articular PRP injection in patients with bilateral early OA knee: A novel technique

Abstract

Purpose: To compare the clinical and functional outcomes of single spin versus double spin platelet rich plasma (PRP) intraarticular injection treatment for patients with bilateral early osteoarthritis knee (OA).Methods: This study was a prospective, comparative, observational, time bound, hospital-based study conducted from November 2018 to August 2019, after obtaining institutional ethical committee (IEC) approval. The study involved 32 patients affected by bilateral OA knee. The patients were treated with single spin PRP injection in one knee and double spin PRP injection in the other knee in the same patient. The knee to which single spin or double spin PRP injection was to be given was picked using a simple randomization technique. The patients were evaluated at the time of presentation before intraarticular injection and at 1, 3 and 6 months follow-up with WOMAC, VAS and Oxford Knee scores.Results: Patients were assessed before the first injection and after the intraarticular injection with a follow-up at 1 month, 3 months and 6 months. VAS score decreased after single spin PRP, by 3.94 points (p