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Treatment With Platelet-Rich Plasma Is More Effective Than Placebo for Knee Osteoarthritis

The American Journal of Sports Medicine · 2013 · Vol. 41(2) · pp. 356–364

Sandeep Patel(Post Graduate Institute of Medical Education and Research)Mandeep Singh Dhillon✉(Post Graduate Institute of Medical Education and Research)Sameer Aggarwal(Post Graduate Institute of Medical Education and Research)Neelam Marwaha(Post Graduate Institute of Medical Education and Research)Ashish Jain(Post Graduate Institute of Medical Education and Research)

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Abstract

A single dose of WBC-filtered PRP in concentrations of 10 times the normal amount is as effective as 2 injections to alleviate symptoms in early knee OA. The results, however, deteriorate after 6 months. Both groups treated with PRP had better results than did the group injected with saline only.

Periodontal Regeneration and Treatments Osteoarthritis Treatment and Mechanisms Knee injuries and reconstruction techniquesMedicinePlatelet-rich plasmaWOMACOsteoarthritisVisual analogue scalePlaceboRandomized controlled trialGroup BSurgerySaline

MeSH terms

AdultAgedAged, 80 and overDouble-Blind MethodFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeOsteoarthritis, KneePlatelet-Rich Plasma

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752

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References

Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee

Arthritis & Rheumatism · 1986 · 6,725 citations

Platelet‐Rich Plasma Intra‐Articular Injection Versus Hyaluronic Acid Viscosupplementation as Treatments for Cartilage Pathology: From Early Degeneration to Osteoarthritis

Arthroscopy The Journal of Arthroscopic and Related Surgery · 2011 · 576 citations

Comparative study of clinical and functional outcome of treatment of mild to moderate osteoarthritis of knee joint between intra articular platelet rich plasma and Hyaluronic acid injection

International Journal of Orthopaedics Sciences · 2020 · 2 citations

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