review Open AccessTop 1% cited
SARS-CoV-2 variants, spike mutations and immune escape
Nature Reviews Microbiology · 2021 · Vol. 19(7) · pp. 409–424
William T. Harvey(MRC University of Glasgow Centre for Virus Research)Alessandro M. Carabelli(University of Cambridge)Ben Jackson(University of Edinburgh)Ravindra K. Gupta(University of Cambridge)Emma C. Thomson(Wellcome Sanger Institute)Ewan M. Harrison(University of Cambridge)Catherine Ludden(University of Cambridge)Richard Reeve(University of Glasgow)Andrew Rambaut(University of Edinburgh)Sharon J. Peacock(University of Cambridge)David L. Robertson✉(MRC University of Glasgow Centre for Virus Research)
SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesSARS-CoV-2 detection and testingBiologyAntigenicityContext (archaeology)MutationVirusGeneticsAntigenic variationPopulationVirologyCoronavirus
MeSH terms
COVID-19SARS-CoV-2COVID-19 VaccinesAmino AcidsEpitopesAntigenic VariationHumansMutationProtein ConformationImmune EvasionSpike Glycoprotein, Coronavirus
Funding
- Wellcome Trust
- UK Research and Innovation
- National Institute for Health and Care Research
- University of Glasgow
- Directorate for Biological Sciences
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
Citations
3,809
FWCI
224.26
field-weighted impact
References
111
Percentile
100%
vs. same field & year
Citations per year
References
A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
Molecular Cell · 2020 · 2,057 citations
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus
Cell · 2020 · 4,457 citations
SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects
Nature Structural & Molecular Biology · 2020 · 619 citations
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
eLife · 2020 · 1,457 citations
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