article Open AccessTop 10% cited
PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens
Journal of Antimicrobial Chemotherapy · 2017 · Vol. 72(10) · pp. 2764–2768
Ea Zankari(Technical University of Denmark)Rosa Lundbye Allesøe(Technical University of Denmark)Katrine Joensen(Statens Serum Institut)Lina Cavaco(Technical University of Denmark)Ole Lund(Technical University of Denmark)Frank M. Aarestrup✉(Technical University of Denmark)
Abstract
PointFinder proved, with high concordance between phenotypic and predicted antimicrobial susceptibility, to be a user-friendly web tool for detection of chromosomal point mutations associated with antimicrobial resistance.
Antibiotic Resistance in BacteriaBacteriophages and microbial interactionsPlant Pathogenic Bacteria StudiesAntimicrobialPoint mutationMicrobiologyAntibiotic resistanceBiologyGeneticsComputational biologyBacteriaMutationGene
MeSH terms
Anti-Bacterial AgentsChromosomes, BacterialEnterobacteriaceaeErythromycinEscherichia coliMicrobial Sensitivity TestsPhenotypeSoftwareTetracyclinesQuinolonesCampylobacter jejuniGenome, BacterialPoint MutationSequence Analysis, DNAMacrolides
Funding
- Strategiske Forskningsråd
- Center for Genomic Epidemiology
Citations
779
FWCI
7.62
field-weighted impact
References
37
Percentile
99%
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References
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Antimicrobial Agents and Chemotherapy · 2013 · 2,238 citations
Quinolone and Macrolide Resistance in Campylobacter jejuni and C. coli: Resistance Mechanisms and Trends in Human Isolates
Emerging infectious diseases · 2001 · 698 citations
ARG-ANNOT, a New Bioinformatic Tool To Discover Antibiotic Resistance Genes in Bacterial Genomes
Antimicrobial Agents and Chemotherapy · 2013 · 1,459 citations
Real-Time Whole-Genome Sequencing for Routine Typing, Surveillance, and Outbreak Detection of Verotoxigenic Escherichia coli
Journal of Clinical Microbiology · 2014 · 1,403 citations
Identification of acquired antimicrobial resistance genes
Journal of Antimicrobial Chemotherapy · 2012 · 5,069 citations
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