review Open AccessTop 1% cited
Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis
Intensive Care Medicine · 2020 · Vol. 46(8) · pp. 1552–1562
Carolin Fleischmann-Struzek(Jena University Hospital)Lisa Mellhammar(Lund University)Norman Rose(Jena University Hospital)Alessandro Cassini(World Health Organization)Kristina E. Rudd(University of Pittsburgh)Peter Schlattmann(Jena University Hospital)Benedetta Allegranzi(World Health Organization)Konrad Reinhart✉(Humboldt-Universität zu Berlin)
Abstract
Compared to results from the IHME study, we found an approximately 50% lower incidence of hospital-treated sepsis. The majority of studies included were based on administrative data, thus limiting our ability to assess temporal trends and regional differences. The incidence of sepsis remains unknown for the vast majority of LMICs, highlighting the urgent need for improved epidemiological sepsis surveillance.
Sepsis Diagnosis and TreatmentNosocomial Infections in ICUNeonatal and Maternal InfectionsMedicineSepsisIncidence (geometry)Meta-analysisAnesthesiologyPopulationEmergency medicineIntensive care medicineInternal medicinePediatrics
MeSH terms
AdultHospitalsHumansIntensive Care UnitsIncidenceSepsis
Funding
- World Health Organization
Citations
943
FWCI
54.98
field-weighted impact
References
52
Percentile
100%
vs. same field & year
Citations per year
Cited by
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021
Critical Care Medicine · 2021 · 2,612 citations
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021
Intensive Care Medicine · 2021 · 4,693 citations
References
Improved tests for a random effects meta‐regression with a single covariate
Statistics in Medicine · 2003 · 1,920 citations
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
Critical Care Medicine · 2001 · 8,573 citations
Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement
Journal of Clinical Epidemiology · 2012 · 2,512 citations
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
Critical Care Medicine · 2003 · 5,994 citations
Assessment of Global Incidence and Mortality of Hospital-treated Sepsis: Current Estimates and Limitations
American Journal of Respiratory and Critical Care Medicine · 2015 · 3,532 citations
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
JAMA · 2016 · 27,000 citations
Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis
CHEST Journal · 1992 · 13,160 citations
Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study
The Lancet · 2020 · 7,270 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.